(R)-(+)-2-PHENOXYPROPIONIC ACID

(R)-(+)-2-PHENOXYPROPIONIC ACID - Names and Identifiers

Name	(R)-(+)-2-PHENOXYPROPIONIC ACID
Synonyms	R-PPA D-Lactic acid phenyl ether (R)-2-PHENOXYPROPIONIC ACID (2R)-2-Phenoxypropanoic acid (2R)-2-phenoxypropanoic acid (2R)-2-Phenoxypropionic acid (R)-(+)-2-PHENOXYPROPIONIC ACID [R,(+)]-2-Phenoxypropanoic acid Propanoic acid,2-phenoxy-, (2R)-
CAS	1129-46-0
InChI	InChI=1/C9H10O3/c1-7(9(10)11)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,10,11)/t7-/m1/s1

(R)-(+)-2-PHENOXYPROPIONIC ACID - Physico-chemical Properties

Molecular Formula	C9H10O3
Molar Mass	166.17
Density	1.174±0.06 g/cm3(Predicted)
Melting Point	84-86 °C
Boling Point	265.0±0.0 °C(Predicted)
Flash Point	112.7°C
Vapor Presure	0.00471mmHg at 25°C
pKa	3.22±0.10(Predicted)
Refractive Index	1.53

(R)-(+)-2-PHENOXYPROPIONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

(R)-(+)-2-PHENOXYPROPIONIC ACID - Introduction

(R)-2-Phenoxypropionic acid is an organic compound with the chemical formula C9H10O3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance:(R)-2-Phenoxypropionic acid is a colorless or slightly yellow liquid.
-Melting point: about 20-25 degrees Celsius.
-Boiling point: about 205-208 degrees Celsius.
-Density: about 1.192g/cm3.

Use:
(R)-2-phenoxypropionic acid has important application value in the field of organic synthesis, and is commonly used in the preparation of biologically active compounds, such as pharmaceutical intermediates and important raw materials for chemical synthesis.

Preparation Method:
The preparation of (R)-2-phenoxypropionic acid can be carried out by the following steps:
1. Recrystallize terephthalic acid and react with dimethyl sulfoxide at high temperature to generate dimethyl terephthalate.
2. Dimethyl terephthalate is reacted with sodium baccate and (R)-(-)-α-phenylethylammonium bromide under alkaline conditions to produce (R)-( )-2-phenoxypropionic acid.

Safety Information:
(R)-2-phenoxypropionic acid is generally considered to be a relatively safe compound, but appropriate safety measures still need to be taken:
-Irritating to skin and eyes, rinse with plenty of water immediately after contact.
-When handling the compound, appropriate precautions should be taken, such as wearing gloves, goggles and protective clothing.
-During storage and use, avoid contact with oxidants and strong acids to avoid the production of hazardous substances.
-When using the compound, you should follow the correct operating procedures and conduct the experiment under well-ventilated conditions.

Please note that this is only a general introduction to (R)-2-phenoxypropionic acid, and the specific situation needs to be evaluated and operated in detail in combination with practical applications and relevant safety data.

Last Update：2024-04-09 15:17:51